The following organizations currently represent the clients of the Institute of the Information Society:

• Administration of Republic of Mordovia 
• Alt Linux Technology
• All-Russian Institute for Scientific and Technical Information
• ARS Communications
• B.A.C.
• Blagonravov Institute of Mechanical Engineering of the Russian Academy of Sciences
• British Council Russia
• Center of Informatization of the Cultural Sphere 
• Center of Economic and Legal Initiatives (Nonprofit Partnership)
• COMCOR-INET
• Economika 
• e-Moscow company
• Governing Center for Social Projects
• Hewlett-Packard (JSC)
• Information Business Systems (IBS)
• “Informexpertise” Project Implementation Group
• Institute of Economics of the Russian Academy of Sciences 
• Institute of Modern Development (formerly Information Society Development Center, RIO-Center)
• Institute of Organic Chemistry of the Russian Academy of Sciences named after N.D. Zelinsky
• Institute of Oriental Studies of the Russian Academy of Sciences
• Institute of the Petrochemical Synthesis of the Russian Academy of Sciences named after A.V. Topchiev
• International Bank for Reconstruction and Development
• IT. Information Technologies Firm (CJSC) 
• Ivanovo State University
• Kazan State University
• Koltzov Institute of Developmental Biology of the Russian Academy of Sciences
• Landau Institute for Theoretical Physics
• Main Datacenter of the Ministry of Culture of the Russian Federation (Federal State Unitary Enterprise)
• Ministry of Culture and Mass Communications of the Russian Federation
• Ministry of Economic Development of the Russian Federation
• Ministry of Information Technologies and Communications of the Russian Federation
• Moscow City Duma (Council)
• Moscow City Government (Committee of Outdoor Advertisement and Information)
• Moscow City Government (Department of Culture)
• Moscow City Government (Department of Economic Policy and Moscow City Development)
• Moscow City Government (Department of Education)
• Moscow City Government (Department of International Relations)
• Moscow City Government (Moscow City Informatization Sector)
• Moscow City Government (Moscow City Sector Governing the Activities of the Justices of the Peace)
• Moscow Committee of Science and Technologies
• Moscow Power Engineering Institute (Technical University) - MPEI
• Moscow Scientific and Research Center (federal institution)
• Moscow Social Register (State Unitary Enterprise of the Moscow City)
• Moscow State Forest University
• Moscow Telecommunications Corporation COMCOR
• National Center for Education Development
• National Information Technologies (JSC), Republic of Kazakhstan
• National Foundation for Personnel Development
• Nesmeyanov Institute of Organoelement Compounds of the Russian Academy of Sciences  
• Network of Chernogolovka Science Center of the Russian Academy of Sciences
• Oracle Netherlands
• Perm Region Government (Information and Computing Center)  
• Prognoz (CJSC)
• Project Harmony, Inc. (USA nonprofit corporation) – Russian branch office
• RosBusinessConsulting (RBC)
• Russian e-Development Foundation
• Russian Association of Electronic Communications
• Russian Federal Agency for Information Technologies
• Russian Federal Agency for Culture and Cinematography (up to 2008)
• Russian Federal Agency for Education
• Russian Foundation for Fundamental Research
• Russian Humanitarian Scientific Foundation
• Russian State Public Scientific and Technical Library
• Scientific and Research Institute of the Information Technologies (Moscow)
• Scientific Center of Nonlinear Wave Mechanics and Technology of the Russian Academy of Sciences
• South Ural State University
• Study and Research Center on Information and Analytical Work
• Tatarstan Republic Center for Information Technologies
• Tver Region Government (Department of Transportation and Communication)
• Vologda Scientific and Coordinating Center of the Central Economics and Mathematics Institute of the Russian Academy of Sciences
 
• Voronezh Region Administration
• World Bank Institute
• Yaroslavl State University named after P.G. Demidov